New XSeed Labs Research Team Starts Activity in the U.S. in Collaboration With Boehringer Ingelheim

A new research team at XSeed Labs – a collaboration between BioMed X and Boehringer Ingelheim, will develop disease models to understand wound healing and fibrosis.

RIDGEFIELD, CT / ACCESSWIRE / May 16, 2024 / XSeed Labs – a collaboration between BioMed X and Boehringer Ingelheim, announces the start of its first research team on the Boehringer Ingelheim campus in Ridgefield, Connecticut. This research team’s main objective is to develop complex, physiologically relevant disease models that deepen our understanding of dysfunctional wound healing and fibrosis. The end goal is to study fibrosis, drug delivery strategies, and drug safety in parallel, in an effort to bridge the gap between research and development to improve patient outcomes accurately and efficiently.

The new research team is led by Dr. Lorenzo Talà, Group Leader at XSeed Labs. "Due to insufficient understanding of the mechanisms driving their pathology, therapies to treat fibrotic diseases are limited. The aim of our research group is to develop physiologically relevant in vitro and in silico fibrosis models. By combining both approaches, we will interrogate disease mechanisms, identify drug delivery pathways, and assess drug safety in order to facilitate drug development toward resolving fibrotic tissues."

Christian Tidona, Founder and Managing Director of the BioMed X Institute: "We are pleased that we could successfully translate the innovation model we established in Heidelberg and New Haven to work inside a major pharma research and development campus. We have a long history of successful collaboration with Boehringer Ingelheim at our Heidelberg institute, and we are proud to extend this collaboration to their U.S. headquarters in Ridgefield, Connecticut."

"We are committed to accelerating innovation across fibrotic diseases. This partnership allows us to harness top talent across the biomedical industry and leverage our leading research and development site in the U.S. to discover insights that could help transform the way we treat these diseases," said Carine Boustany, PhD, U.S. Research Site Head and Global Head of Immunology and Respiratory Diseases Research, Boehringer Ingelheim. "In parallel, we will harness these innovative disease model systems to assess the safety of novel anti-fibrotic concepts, and identify better ways to deliver our molecules," said Xiaorong He, PhD, U.S. Development Site Head and Global Head of Development Sciences, Boehringer Ingelheim.

"We are excited to start our first XSeed Labs team at Boehringer Ingelheim in Ridgefield. It is the beginning of a unique innovation model that promotes scientific exchange between major players in biomedical research," says Mark Johnston, CEO of BioMed X USA.

About BioMed X and XSeed Labs

BioMed X is an independent research institute with sites in Heidelberg, Germany, New Haven, Connecticut, XSeed Labs in Ridgefield, Connecticut, and a worldwide network of partner locations. Together with our partners, we identify big biomedical research challenges and provide creative solutions by combining global crowdsourcing with local incubation of the world’s brightest early-career research talents. Each of the highly diverse research teams at BioMed X has access to state-of-the-art research infrastructure and is continuously guided by experienced mentors from academia and industry. At BioMed X, we combine the best of two worlds — academia and industry — and enable breakthrough innovation by making biomedical research more efficient, more agile, and more fun.

BioMed X started working with Boehringer Ingelheim in 2015 with a series of joint research projects hosted by the BioMed X Institute in Heidelberg, Germany. The new collaboration model – called XSeed Labs – entails an open innovation incubator embedded in the Boehringer Ingelheim Ridgefield campus in Connecticut, USA.

Contact Information

Flavia-Bianca Cristian
Recruiting & Communications Manager
fbc@bio.mx
+49 6221 426 11 706

Swathi Lingam
Scientific Communication & Editorial Associate
lingam@bio.mx
+49 6221 426 11 27

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SOURCE: BioMed X Institute & XSeed Labs

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DEXIS Innovation Continues With New DEXIS Ti2 Sensor as Successor to the DEXIS Titanium Sensor, the #1 Selling Intraoral Sensor in the United States

QUAKERTOWN, PA / ACCESSWIRE / May 16, 2024 / Today, DEXIS launches the latest innovation in its digital ecosystem with an all-new dental intraoral sensor, the DEXIS™ Ti2 Sensor. The DEXIS digital ecosystem is a comprehensive, AI-powered platform for dental imaging, designed to connect and streamline digital workflows for enhanced productivity.

DEXIS Ti2 Sensor
DEXIS Ti2 Sensor
DEXIS Ti2 Sensor

The Ti2 sensor builds on the success of its predecessor, the DEXIS™ Titanium Sensor, the #1 digital intraoral sensor in the United States.* In 2023, DEXIS sensors processed over 167 million images, making it a top choice for intraoral sensors and scanners, as well as x-ray and CBCT technology worldwide.

Bringing several new features to the DEXIS 2D imaging portfolio, the Ti2 sensor includes:

  • A housing design that’s twice as durable as previous generations
  • A proactive servicing module
  • Access to 2D AI Dental Findings that automatically detect up to six types of dental findings on 2D radiographs

With DEXIS, 2D AI Dental Findings are integrated into both DTX Studio™ Clinic and DEXIS Imaging Suite software-not a separate third-party application. 2D AI Dental Findings automatically identifies periapical radiolucency, bone loss, calculus, caries, discrepancy at margin of existing restoration, and root canal filling deficiency.

"For patients with periodontal disease, we have identified sub-gingival calculus and monitored their bone levels. Caries detection and diagnosis is clear and precise with the contrast available with these images," said Dr. Moe Katz of Katz & Pfeffer Dental Studio.

The Ti2 sensor housing is twice as durable and two times as drop-resistant as the Titanium Sensor. The new posterior holder and WiseAngle™ cable design reduce stress on the sensor/cable connection, further strengthening the Ti2 sensor.

DEXIS also focuses on maximizing the productivity of the dental practice with the newly launched DEXIS Connect Pro. The solution proactively monitors the health of the DEXIS family of sensors through IoT technology and automatically arranges support or equipment replacements if performance issues are ever detected.

"DEXIS Connect Pro provides the kind of customer experience I’ve come to expect from DEXIS," says Amber Metro-Sanchez, dental hygienist at Omni Dental. "The knowledge that my sensor communicates with DEXIS support and that they’re ready to help me if I ever need it gives me peace of mind. They’ve always been so responsive and helpful, DEXIS Connect Pro demonstrates the kind of attention to customer care and continuous innovation I’ve grown accustomed to with DEXIS."

Through the use of CleanCapture™ technology, the Ti2 sensor captures high-resolution images by reducing noise and enhancing anatomical detail. The technology allows the sensor to be flexible and ready to adapt to varying exposure levels, generator usage, or positioning techniques to capture clear, accurate images reliably – even in challenging circumstances.

Equipped with its PerfectSize™ design, the Ti2 sensor is engineered to fit every patient comfortably, making it a convenient, one-size-fits-all solution for busy practices.

Experience the new DEXIS Ti2 Sensor at booth 1665 at CDA South on May 16-18, 2024.

*DEXIS Titanium Sensor- December 2023 SDM US Market Share Data.

About DEXIS 

DEXIS has been a global leading brand in digital radiography for 70+ years. Today, DEXIS has brought together the most trusted brands in 3D imaging, intraoral scanning solutions, and diagnostic software to provide patients with a complete digital diagnostic solution under a brand name. Our innovative award-winning technology enhances how the patient is diagnosed, accelerates the workflow, and delivers simple treatment paths with better patient outcomes. For more information, please visit https://www.dexis.com.

Contact Information:

Hayley Reed
Regional Marketing Director, DEXIS IOS
hayley.reed@envistaco.com
(714) 628-8533

SOURCE: DEXIS

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View the original press release on newswire.com.

(EDITORIAL from Korea Times on May 16)


In the heart of Seoul, amidst the bustling streets and towering skyscrapers, a different kind of battle is being waged — one that resonates far beyond the borders of Korea. This battle is not waged with weapons or political rhetoric, but with the weight of legal arguments and the fervent determination of climate-concerned citizens, passionate activists and lawyers.

At the center of this struggle is Korea’s Constitutional Court, which held the first public hearing of Asia’s first climate lawsuit against the government’s climate target on April 23, with the next hearing scheduled for May 21, a watershed moment in the global fight against the climate crisis.

The genesis of this legal saga dates back to 2020, when the first climate lawsuit was filed in Korea. Now, four consolidated lawsuits stand before the court, each representing a diverse array of plaintiffs united by a common cause: To hold the government accountable for its inadequate climate policies. From infants to children, teens, citizens and civil s
ociety activists, the plaintiffs represent a unified voice demanding climate justice and liability.

The crux of the plaintiffs’ argument rests on a fundamental premise: That climate change is not just an environmental issue, but a matter of constitutional rights. They contend that the government’s failure to address the climate crisis effectively in a timely manner infringes upon their right to life and a clean environment – an assertion bolstered by the Korean National Human Rights Commission’s declaration that climate change constitutes a human rights issue of paramount importance.

Central to the plaintiffs’ case is the disparity between Korea’s national greenhouse gas emission reduction goal and those of other industrialized nations. They argue that the government’s current policies fall woefully short of what is required to mitigate the catastrophic effects of climate change, citing scientific evidence and international legal precedents to support their claims. From inadequate emissions reduction target
s to a reliance on fossil fuels, the government’s approach to climate action is deemed insufficient and incompatible with its constitutional obligations.

However, the government remains steadfast in its defense, citing the complexities of policymaking. While acknowledging the urgency of climate change, government officials argue that the judiciary should not encroach upon matters of policy and governance — a stance that sets the stage for a clash of legal doctrines and raises fundamental questions about the separation of powers.

As the courtroom drama unfolds, the eyes of the world are fixed upon Korea, recognizing the profound implications of this historic legal battle. The outcome of these lawsuits will reverberate across continents, shaping the future of climate action and holding governments accountable for their climate commitments. Indeed, Korea’s climate litigation is not just a domestic affair; it is a global rallying cry for climate justice and a testament to the power of grassroots activism in ef
fecting change.

In recent years, climate litigation has emerged as a powerful tool for holding governments and corporations accountable for their contributions to climate change. From landmark rulings in Europe to groundbreaking lawsuits in the United States, courts around the world have increasingly recognized the urgent need for climate action and the legal obligations of governments to protect the environment and uphold human rights.

Korea’s climate litigation represents a significant milestone in this global movement for environmental justice. By challenging the government’s climate policies in court, plaintiffs are not only seeking redress for past injustices but also demanding systemic change to ensure a sustainable and equitable future for all. Their courage and determination serve as an inspiration to activists and advocates worldwide, galvanizing support for climate action and sparking meaningful conversations about the intersection of law, justice and the environment.

Beyond the legal arguments a
nd constitutional debates lies a deeper truth — a truth that speaks to the moral imperative of safeguarding our planet for future generations. It is a truth embodied by the faces of the youth activists who stand as plaintiffs in this historic case — a generation that refuses to inherit a world ravaged by the climate crisis. Their voices echo a universal call to action, reminding us of our collective responsibility to protect humanity and our planet.

In the end, Korea’s climate litigation is not just about winning a legal battle; it is about winning the fight for humanity’s future. It is about affirming our commitment to climate justice and ensuring that the voices of the marginalized and the disenfranchised are heard and heeded. As the judges of the Constitutional Court deliberate and the plaintiffs await their verdict, one thing remains abundantly clear: The world is watching, and the time for action is now.

Source: Yonhap News Agency

DOF proposes sale of SCTEX shares to SSS, GSIS

MANILA: Finance Secretary Ralph Recto said the interest of the Bases Conversion and Development Authority (BCDA) in the Subic-Clark-Tarlac Expressway (SCTEX) could also be sold to the Social Security System (SSS) and the Government Service Insurance System (GSIS).

“We’re looking at selling those shares. Maybe the SSS and GSIS can buy them. Para kumita pa yung pension fund (So the pension fund will earn). I think it’s a good deal,” Recto told reporters in an interview on Tuesday.

“I think we have other shares that we’re privatizing. The government has a few shares. And I think it’s better off that we sell those shares to raise revenue, non-tax revenue, and better siguro (maybe) the pension funds buy from us. Para makinabang naman yung SSS at GSIS (So the GSIS and SSS will benefit),” he added.

The BCDA earlier said that the Metro Pacific Tollways Corp. (MPTC) has formally submitted a proposal to acquire the government’s stake in SCTEX after it submitted a letter to the BCDA, the Department of Finance, and Ma
lacanan Palace.

Finance Undersecretary for Privatization and Corporate Affairs group Catherine Fong in a Viber message said that if the BCDA sells its shares, the DOF prefers it to be offered to the pension funds.

“Assuming BCDA agrees to sell it, we prefer it be offered to the pension funds first. Because if they can afford to buy and hold it, they will reap the dividends and the value for the benefit of the pensioners. They may choose to flip it later on,” said Fong.

“This will be decided by the BCDA,” he added.

Source: Philippines News Agency

Gov’t agencies sign pact with Roxas City to curb illegal recruitment

MANILA: The Department of Migrant Workers (DMW) and the Overseas Workers Welfare Administration (OWWA) on Thursday signed an agreement with the local government of Roxas City in Capiz to curb illegal recruitment and trafficking in persons.

In a statement, the OWWA said the signed convergence memorandum of agreement (MOA) provides for coordinated actions to strengthen the fight against these illegal acts that target those planning to work overseas.

Other government agencies that signed the MOA include the Department of Labor and Employment (DOLE), the Technical Education and Skills Development Authority (TESDA), and the City of Roxas, Capiz.

“Sa ilalim ng kasunduang ito, plano ng mga ahensya na palakasin ang mga programa at proyekto na maglalayong labanan ang mga aktibidad na ito, pati na rin ang pagpapalakas ng kaalaman at kamalayan ng publiko (Under this partnership, the agencies plan to strengthen programs and projects that aims to fight perpetrators of these activities, and strengthen information dissem
ination and public awareness),” the statement reads.

OWWA Administrator Arnell Ignacio led the signing ceremony together with TESDA Representative Rick Abraham, DOLE Representative Mary Chris Medina, Assistant Secretary for Licensing and Adjudication Services Francis Ron De Guzman, and Roxas City, Capiz Mayor Ronnie Dadivas.

Meanwhile, OWWA distributed livelihood assistance to 15 beneficiaries of its Balik Pinas Balik Hanapbuhay Program (BPBH).

The program aims to provide immediate assistance to returning member OFWs who want to start their own business.

Each beneficiary received PHP20,000 initial capital, the OWWA said.

The BPBH is part of OWWA’s reintegration program that provides cash grants to active or non-active OWWA members who were displaced by hostilities or wars/political conflicts, policy reforms or changes by host governments; victims of illegal recruitment or human trafficking or other distressful situations.

Source: Philippines News Agency

APEC GDP expands 3.5% in 2023, uncertainties loom large

JAKARTA: Growth in the 21-member regional economic group Asia-Pacific Economic Cooperation (APEC) rose by 3.5 percent in 2023 from 2.6 percent in 2022, but a moderation is forecast in 2025 and 2026 due to geopolitical uncertainties.

This was included in the latest report by the APEC Policy Support Unit (PSU), a release issued by the APEC Secretariat and received here on Thursday.

“APEC’s economic growth is outpacing the 3.2 percent global growth. Government spending as well as the health services sector, especially the solid recovery of travel and tourism, have also contributed to this expansion,” Carlos Kuriyama, director of the APEC Policy Support Unit, said.

“However, we are seeing a moderation in economic growth in 2025 and 2026 due to geopolitical uncertainties, trade protectionism, and fluctuations in commodity prices,” he said.

He affirmed that such challenges call for stronger multilateral cooperation between APEC member economies.

Inflation rate has eased steadily, posting an average of 3.9 perc
ent last year as compared to 5.9 percent in 2022. It is expected to decrease further to 2.9 percent this year. However, the report cautioned economies not to let their guards down.

‘With inflation showing signs of moderation, economies are expected to lean toward easing their monetary policy rates to support growth,’ Rhea Hernando, an analyst with the Policy Support Unit, said.

‘Nevertheless, economies need to stay alert to dampen inflationary pressures that could come from possible supply chain disruptions, such as reduced crude stock in key oil-producing economies, alongside ongoing geopolitical issues as well as exchange rate movements,’ Hernando cautioned.

The report said that in the past 12 months, 17 currencies in the APEC region have depreciated against the US dollar, ranging from -2.1 percent to -16.7 percent as of April 2024.

Another development to watch out for is the extended drought and increased maritime risks observed at the Panama and Suez Canals.

These choke points have led to a significa
nt escalation in freight costs, reaching their peak in late January of 2024 and persisting at levels 50 percent higher than usual as of April 2024 as compared to a year ago.

“Uncertainties have dampened trade activity in 2023, affecting spending decisions and causing sluggish demand,” Glacer Niño Vasquez, a researcher with the Policy Support Unit, said.

“Accumulation of restrictive and unpredictable trade policies, such as anti-dumping measures, tariffs, and countervailing duties, continued to increase, which can further curb trade activity,” he added.

Trade numbers are reported to have contracted in 2023, although the report foresees a rebound on the horizon.

The volume of APEC’s merchandise exports grew marginally by 0.3 percent, while imports contracted by 1.4 percent. The value of merchandise trade fell by -6 percent for exports and -6.7 percent for imports.

“Looking ahead, strengthening cooperation in the face of uncertainties is critical to overcoming obstacles and continuing the progress toward su
stainable and inclusive growth that we have made since the Covid-19 pandemic,” Kuriyama said.

“By remaining vigilant, reducing debt and rebuilding buffers, implementing productivity-enhancing structural reforms, and deepening cooperation, APEC economies can effectively navigate the complexities of the current landscape, strengthening economic fundamentals and regional ties for a future that is inclusive, sustainable, and prosperous,” he added.

Source: Philippines News Agency